John, a happily married financial officer, has gone missing. Did the pressure of an audit drive him over the edge, or has something sinister happened? S2/Ep14
Popular teacher and beauty queen Tara is missing. The only clue is an abandoned latex glove found in her backyard. Is an unstable male student involved? S2/Ep16
A month after 17-year-old Kara goes missing, Kelsey is abducted in a car park. When a body is discovered by a lake, two families are locked in a grim waiting game. S2/Ep18
When Amy disappears, police have a suspect but no crime scene, no body and no evidence. It takes an unexpected informant to blow the case wide open. S1/Ep11
A blues guitarist vanishes, leaving few clues to his whereabouts. The case goes cold, until a series of events thrusts it back into the limelight. S1/Ep10
Colleen sails into the sunset with her boyfriend Jean Paul on his luxury yacht - and is never heard from again. Has she fallen foul of her shifty lover's quick temper? S5/Ep85
A young woman on the brink of starting her dream job disappears, and it's down to forensic officers to gather the clues that may lead to her whereabouts. S1/Ep8
When popular park ranger Randy goes missing in the Sierra Nevada Mountains his colleagues work tirelessly to locate him. But will Randy be found alive? S5/Ep84
Billy disappears just after finding out his girlfriend is cheating on him. Is she behind it, or will a perpetrator emerge from beyond the grave? S1/Ep5
In the years following the disappearance of two sixteen-year-old girls, two serial killers separately confess to the murders. Are they toying with police? S5/Ep80
A teenage boy runs away after a fight with his grandma; years later a disorientated young man with amnesia is taken in by concerned strangers. Is this Jarrod? S5/Ep79
Aspiring actress Satara is hooked on heroin and in an abusive relationship with a suspected human trafficker when she goes missing. Where is she now? S5/Ep77
Tracey Ocasio is missing and when one of her boots is found in woodland detectives fear the worst. Is the vicious assault of another young woman connected to her case? S5/Ep76
Bethany is pregnant with her lover's baby when she goes missing. Police speak to her cuckolded husband and her new lover; but are they both telling the truth? S5/Ep75
Street-smart urbanite Shannon goes missing on the remote southern shores of Long Island after making a desperate emergency call. What happened to her? S5/Ep67
When Alexis reports his ex-girlfriend missing, police tell him her house burned down that morning, and that his son died in the blaze. But where is Joey Lynn? S4/Ep65
When 19-year-old Computer Science student Suzy doesn't return home after work, her boyfriend raises the alarm. What happened to Suzy, and will she ever be found? S4/Ep64
Police believe Ben McDaniel disappeared during a cave dive. But the best divers search for his body and cannot find it. Baffled, investigators start questioning his disappearance. S4/Ep63
Clinton has a heart condition, is worried about a narcotics charge, and is unsure if he's about to be a dad when he disappears. Has he run away - or come to harm? S4/Ep62
Recovering drug addict Danice Day disappears, leaving her two young children behind. Did the pressure of sobriety become too much, or has someone harmed her? S4/Ep45
Susan Walsh was a reporter by day, stripper by night. When she disappears, investigators do not know where to begin. But her loved ones insist that she would never leave her son. S4/Ep59
Student Charlie Allen is due to meet a friend but never shows up. The day he disappears, he tells his sister people are after him. But is Charlie truly in any danger? S4/Ep43
When Jamie Fraley vanishes from her apartment, detectives suspect her boyfriend's obsessive father is involved. However, a grim discovery changes the course of the investigation. S4/Ep51
Morgan Harrington is separated from her friends at a rock concert and lost. Clues lead nowhere, until a forensic team links the case to a separate violent crime. S4/Ep42
Ginni Wood loses contact with her mother while on a road trip to visit her best friend in Texas. The mystery deepens when the best friend goes missing as well. S4/Ep50
Steven Koecher's car is found abandoned near Las Vegas and no one has heard from him. A clean-cut church-goer, he is not the type to simply go missing. What happened to him? S4/Ep41
A feisty trucking company manager vanishes from her home without a trace. The case takes a terrifying turn when her purse is found near the lair of a serial killer. S4/Ep49
Firefighter Margaret McEnroe disappears, leaving behind her daughter. Police know that Margaret has a temper - but also maternal instincts. How could she vanish without a trace? S4/Ep57
Tammy disappears after leaving work. Her relatives find a note saying she's gone for a walk, but searches yield no signs. What happened to Tammy? S7/Ep10
Robert fails to pick up his wife at the airport, and his son tells investigators how he met some shady men days earlier. What made Robert disappear? S7/Ep9
Former Harlem Globetrotter Rico Harris is driving to Seattle and mysteriously vanishes. Investigators embark on a journey that grows more baffling as time passes. S7/Ep8
David attends one final meeting before driving home to visit his family. But soon after, his truck is found abandoned. How did David just vanish into thin air? S7/Ep7
Brandy leaves work on Friday afternoon for the weekend but fails to show up for work on Monday morning. Did she walk away from her rocky love life? S7/Ep6
Days after Jennifer Kesse goes missing, her car is found abandoned near her home. A decade later her disappearance remains one of Florida's most baffling crimes. S7/Ep5
Brian, a 25-year-old BMX rider, was last seen wandering in a field. Have Brian's risky bike moves led to a severe state of confusion and his disappearance? S7/Ep4
An artist disappears on her way home from work. When her car is found abandoned in a car park, it sets off some dark speculation about her disappearance. S7/Ep3
Jessica is working the night shift at a petrol station. When a customer arrives to find the shop empty, investigators believe she's been abducted. S7/Ep2
TV news anchor Jodi Huisentruit fails to show up to work one morning and police are called to an alarming scene at her apartment, where they uncover troubling details. S5/Ep83
Amy goes for a run in the forest and vanishes without a trace. The investigation into her mysterious disappearance spans years and hundreds of square miles. S5/Ep82
When an exotic bird ranch is abandoned, leaving uncertain the fate of 700 valuable birds, a bizarre mystery unfolds. The search for the missing owners begins. S5/Ep81
Follow police investigators as they attempt to crack mysterious missing-persons cases. Did the victims voluntarily vanish, or is there evidence of foul play? S5/Ep80
A teenage boy runs away after a fight with his grandma. Years later, a disorientated young man with amnesia is taken in by concerned strangers. Is this Jarrod? S5/Ep79
A young bellhop goes missing on a treasure hunting trip in the Arizona wilderness. Will rescuers find Jesse, or is he another victim of the Dutchman's Curse? S5/Ep78
Aspiring actress Satara is hooked on heroin and in an abusive relationship with a suspected human trafficker when she goes missing. Where is she now? S5/Ep77
Tracey Ocasio is missing; when one of her boots is found in woodland, detectives fear the worst. Is the vicious assault of another young woman connected to her case? S5/Ep76
Bethany is pregnant with her lover's baby when she goes missing. Police speak to her cuckolded husband and her new lover - but are they both telling the truth? S5/Ep75
Matrice is arrested when she can't pay her restaurant bill, but after cops release her into the night without her car, keys, or cash, she disappears. Where is she? S5/Ep74
Big game hunter Bob is fooled by a predatory con artist and puts a $1000 deposit on a non-existent Thunderbird, but will his search for his money end well? S5/Ep73
After a 59-year separation, Bob and Fontelle marry following a whirlwind reunion. But two days before Fontelle relocates to California, Bob disappears - where is he? S5/Ep71
When millionaire Billy McGrath disappears and someone starts impersonating him through emails, his advisor alerts the police - who go on to uncover a shocking plot. S5/Ep70