A tumultuous relationship with her husband caused Tamy Lyn's weight to reach more than 500lbs. Isolated from the outside world, she needs to restart her life. S6/Ep8
Joe is only 30, and trapped in an 800-lb body. He lost his job and is mostly housebound. Can Joe find the strength to face his past and save his life? S3/Ep5
At just 24, Bettie Jo is eating her way towards 700-lbs. Housebound, she is reliant on her husband for even basic needs. But can she shed the pounds? S3/Ep4
To cope with the emotional turmoil of his childhood, 23-year-old Chay has eaten his way to 600-lbs - and it's threatening to kill him before turning 30. S3/Ep10
Destinee never felt like she fit in, as she was born Matthew. She has come out as a transgender woman but needs to lose weight, so she can fully transition. S7/Ep20
Destinee never felt like she fit in, as she was born Matthew. She has come out as a transgender woman but needs to lose weight, so she can fully transition. S7/Ep19
Brittani married a man who loves large women but at 600 lbs she can barely contribute to their marriage. After surgery, she must forge a new life. S4/Ep4
At 670 pounds, Ashley is desperate to save her life and her marriage to husband David. Can weight-loss surgery give her the chance for a family of her own? S5/Ep2
At nearly 700 lbs Pauline has an addiction to food that is killing her and taken over the life of her son. Can she overcome it and save both their lives? S3/Ep3
Siblings Robin and Chris are both obese and have lost a sibling to obesity. Now, Chris's son Garrett, already 600lbs at age 20, wants to lose weight. S7/Ep6
Siblings Robin and Chris are both obese and have lost a sibling to obesity. Now, Chris's son Garrett, already 600lbs at age 20, wants to lose weight. S7/Ep5
At over 600 lbs, Susan is committed to drastic weight loss. But when a medical disorder strikes her mobility, her plight becomes a matter of life and death. S3/Ep2
At age 23, and over 600 lbs, Amber relies on her family for even simple needs. Her fear of dying young sends her 2,000 miles for weight loss surgery. S3/Ep1
Marla is so heavy she cannot stand up. Bedridden, she must face the facts about her health and the toll it takes on her supportive family, if she is to save her health. S3/Ep9
Despite a solid support network of her boyfriend and cousin, Tiffany struggles to break the cycle of depressed eating when her two roommates don't help her. S7/Ep18
Despite a solid support network of her boyfriend and cousin, Tiffany struggles to break the cycle of depressed eating when her two roommates don't help her. S7/Ep17
At 700 pounds, Chad undergoes gastric bypass surgery. He quickly sheds pounds, but faces a medical crisis when he does not follow the doctor's orders. S4/Ep3
29-year-old twins Brandi and Kandi are close after a traumatic childhood, seeing food as a comfort. But after weight-loss surgery, more challenges await. S5/Ep1
26-year-old Sean weighs over 700-lbs. His mother is forced to change both of their lifestyles before he can be approved for gastric bypass surgery. S4/Ep12
Octavia has been bedbound for nearly a year. But, with her best friend also her worst enabler, can she choose between old habits and a new life? S7/Ep4
Octavia has been bedbound for nearly a year. But, with her best friend also her worst enabler, can she choose between old habits and a new life? S7/Ep3
At 700lbs, Milla is dependent on her husband. Terrified each day will be her last can Milla stop a lifetime of unhealthy eating to qualify for gastric surgery? S4/Ep11
At over 700lbs, Teretha's life is confined to a bed. Her family fears losing her and hopes a gastric bypass will provide the solution she needs to save her life. S4/Ep10
Laura has used food to cope with her emotions for too long. Confined to a wheelchair, she depends upon her husband and mother to survive. Can she turn her life around? S3/Ep8
Maja moves to Houston to begin a difficult weight-loss journey with the support of her boyfriend Christian. But when he abruptly leaves her, she must do it alone. S7/Ep16
Maja moves to Houston to begin a difficult weight-loss journey with the support of her boyfriend Christian. But when he abruptly leaves her, she must do it alone. S7/Ep15
Weighing over 700 pounds at 26-years-old, the clock is ticking on Ashley's life. Ashamed of her body, surgery offers hope, but not without setbacks. S4/Ep2
Tara is single mother of two who feels like a prisoner in her own body. Riddled with joint pain she is determined to lose the weight - and see her kids grow up. S2/Ep8
At 650lbs, Randy's food addiction led to the loss of his marriage and visits with his daughter. To regain control of his life, he endures a rigorous pre-surgery diet. S4/Ep9
At over 700lbs, Brianne is on a weight-loss journey to save her own life. But she faces another shock when her husband's health suddenly deteriorates. S7/Ep2
At over 700lbs, Brianne is on a weight-loss journey to save her own life. But she faces another shock when her husband's health suddenly deteriorates. S7/Ep1
At 600 pounds, Lupe spent the last 10 years in bed. A doctor in Texas is her only hope for change - but did she wait too long to begin her weight-loss journey? S4/Ep8
Suffering from flesh-eating bacteria and weighing almost 800-lbs, Charity relies on her family. When bad news threatens her weight loss can she carry on? S3/Ep7
Brandon is a talented musician and singer but his addiction to food has left him incapacitated, and he risks losing his girlfriend and his career dreams. S7/Ep14
Brandon is a talented musician and singer but his addiction to food has left him incapacitated, and he risks losing his girlfriend and his career dreams. S7/Ep13
Lifelong secret eater Nikki is threatened by immobility as her weight climbs to 650-lbs. She has a gastric bypass and confronts the emotional causes for her eating. S4/Ep1
At 605-lbs, Tracey carries most of her body weight in her misshapen legs, which are so extreme she needs someone to lift them out of bed. Can Dr. Nowzaradan help her? S5/Ep12
Dottie loves being a mom but, at over 600lbs, she's on the verge of leaving her 2 young children motherless. Can she take drastic action and turn her life around? S4/Ep7
At nearly 900lbs Robert is bed-ridden and living in a nursing home, with lymphedema masses on each hip. Can he make the radical life changes needed to save his life? S6/Ep28
At nearly 900lbs Robert is bed-ridden and living in a nursing home, with lymphedema masses on each hip. Can he make the radical life changes needed to save his life? S6/Ep27
At 650 pounds and Desperate for change, Gideon uproots his family to restart his life with weight-loss surgery and hopes for a future of happily-ever-after. S4/Ep6
600-pound June copes with the tragic death of her son by eating. After gastric bypass surgery, she must confront the emotional issues driving her food compulsion. S4/Ep5
At 42 years old, Angel is staring death in the face. She is struggling to make a positive change and be an active part of her partner and son's lives. S3/Ep6
Lacey has ballooned to over 600 lbs. She must now rally her divorced parents around her and find a way to modulate her moods that won't include binge-eating. S7/Ep12
Lacey has ballooned to over 600 lbs. She must now rally her divorced parents around her and find a way to modulate her moods that won't include binge-eating. S7/Ep11
Paula has had a tough life, and at over 600lbs, has built a physical wall around herself to push people away. But can shed the pounds and turn her life around? S2/Ep6