New. Regina is relying on Madge to betray the hospital, Jac needs to find a surgeon who will operate on her risky tumour, and Hanssen discovers another of Billie's secrets. [S]
New. Jac has a couple of requests before she goes under the knife. Josh over-invests in a familiar patient and returning Rev Lexy receives good news about a new kidney. [S]
New. The reverberations of Jac's surgery are felt around Darwin and beyond, Dom feels more left out than ever and Donna and Hanssen rally around Lexy after bad news. [S]
Whose Heart is it Anyway?: The first-ever episode of the medical drama offshoot from Casualty. Surgeons Anton Meyer and Nick Jordan race against time to carry out a transplant operation. [S]
Happy Families: Another slice of life on the wards of Holby City Hospital. Surgeon Nick Jordan is put to the test while nurse Jasmine Hopkins has to use her diplomatic skills. [S]
Vinegar & Honey: Kian's larger-than-life personality and alternative methods begin to grate on Jac. Ange opens up to Dom, revealing a huge secret in the process. [S]
North & South: Zosia and Jac's relationship deteriorates when Jac pulls rank over a patient's treatment, but a startling incident forces them to unite. [S]
The Family Way: Dom throws himself into work as he struggles to process a shocking family secret. Zosia publicly undermines Jac's authority, putting a strain on their relationship. [S]
Ask No Questions: Chloe is wrong-footed when ex-boyfriend Evan turns up on Darwin. As Ange reels from her recent discovery, Dom is also confronted with life-changing revelations. [S]
Running: Ange uncovers a long-buried secret that threatens to completely tear her life apart, while Cameron's attempts to find a date crash and burn - much to the delight of Xavier. [S]
A Simple Lie, Part Two: Fletch worries there may be more to Theo's disappearance than meets the eye, and Chloe's day is thrown off balance when a surprise visitor appears. [S]
A Simple Lie, Part One: The high court gives its judgement on withdrawing care for Ange's patient. Frieda returns to Darwin, but faces problems when she is paired with Zosia for the day. [S]
Guts: Zosia's news gets a mixed response and her situation is further complicated when a colleague from the US turns up. Sacha is rattled when an old flame appears with their partner. [S]
Never Say Never: Zosia returns to Holby looking for work, while a frustrated Jac tries to track down Frieda, and Ange admits there is no hope for her patient, Holly. [S]
Good Side: While Holly's condition weighs heavily on an emotionally invested Ange, Holly's distraught parents must put their differences aside to make a heart-breaking decision. [S]
Force Majeure: A family secret leads to a young patient delaying vital surgery, Ric campaigns for change, and does Nicky have the strength to fight for what she wants? [S]
Twist of the Knife: Mo makes a heart-wrenching decision during a personal emergency, and Nina's judgement is called into question when she oversteps the mark with a patient on AAU. [S]
Enigma: Lofty is unexpectedly confronted with his past and realises that he has to come to terms with the life-changing choices he has made, while Mo is ecstatic to be offered Jac's job. [S]
Project Aurous: Jac's job and livelihood are at risk when a mystery patient arrives on Darwin and seeks her help, and a short-staffed Keller welcomes a new face to the team. [S]
The Heart Is A Small Thing: Matteo wants to prove his marriage is over, but an old face raises memories of his life before Holby - meanwhile, Dominic struggles on his first day back. [S]
Gold Star: Mo finds herself caught between pregnant patient Trixie and Derwood's overbearing mother, and Oliver's eagerness to impress causes friction between Bernie and Ric. [S]
Two Hearts: After uncovering a revelation from Matteo's past, he and Jac clash over a patient - meanwhile, Sacha is not himself, but how long can he keep Essie off the scent? [S]
Past Imperfect: Jac and Matteo's relationship is heading in the right direction, but when she becomes suspicious of his motives, her investigations find skeletons in his closet. [S]
Someone to Look After Me: Dominic and Isaac's toxic relationship reaches breaking point, Fletch's world is shattered by a revelation, and Matteo takes on a seemingly impossible task. [S]
It's Only Love If It Hurts: Serena faces her demons and comes to a heart-wrenching conclusion, Zosia takes action when Isaac reveals his true colours, and Mo risks her reputation. [S]
Unbreakable: Dom and Isaac clash professionally over a patient's treatment, and Serena is dealt a blow when a patient arrives on AAU serving as a reminder of Elinor's recent death. [S]
Growing Pains: Essie is shocked when Parker turns up with a friend, and Zosia is harbouring a secret from Ollie and is horrified to learn that Isaac knows what it is. [S]
Daylight: Mo returns from maternity leave and drops a bombshell, and Dominic gets a shock when he realises that going to Hawaii with Isaac is not going to be straightforward at all. [S]